Sravan Balloji

ESR 9 - Sravan Balloji

Sravan Balloji

India
ESR 9 - “Mitochondrial Biomarkers to Predict Hepatic Surgery Success”
IibB-csic

Biography

I am Sravan Balloji from India. I did my bachelor’s degree with triple major (Biochemistry, Biotechnology and Microbiology) from Andhra university, India and Master’s degree in biochemistry and molecular biology from Pondicherry University, India. My master’s thesis was entitled “Evaluation of anti cancer, anti oxidant and anti microbial properties of cinnamomum tamala extracts”. My desire towards research prompted me to pursue another masters in Protein Science to develop my skills further so I joined International Master’s program in Protein Science and Biotechnology at University of Oulu, Finalnd. I also interned at Neuroscience centre, University of Helsinki, where I worked on physical and functional characteristics of Microglia in different regions of brain in stress mice. I worked for Prof. Kari Alitalo lab located at biomedicum, University of Helsinki, where my work mainly concentrated on endothelial cells of heart and its specialized interactions with other cell types in heart. I am thankful to Project FoieGras network for providing me opportunity to work as early stage researcher at Institute of Biomedical Research of Barcelona, Spanish National Research Council (IIBB-CSIC), Spain.

Summary of ESR Project

My project titled as “Mitochondrial biomarkers to predict hepatic surgery success” the main objective is to predict the outcome of liver surgeries using mitochondrial biomarkers. In order to find that we use animal models of postoperative hepatic failure (PHF) to measure end- points of mitochondrial function at different points after surgery. So by analysing these we can predict the susceptibility to hepatic mitochondrial damage and design the drugs in near future to improve the liver function after surgeries.

Research methodologies will include techniques in liver surgery of rodent models, miRNA/mtDNA screening, and high throughput mitochondrial function assays(e.g. respiration, membrane potential, oxidative stress and mitochondrial gene expression), as well as provide IR fingerprint in serum by IR-based methods.

Supervisor:

Dr. Joan Catafau

Secondments:

German Research Center for Environmental Health (HMGU), Germany
Center for Neuroscience and Cell Biology (CNC), Portugal

Co-Supervisors:

Dr. Hans Zischka
Dr. Carlos Palmeira
Dr. Paulo Oliveira