Work Package Leader: Center for Neuroscience and Cell Biology (CNC, Portugal)
WP2 will promote cross-pollination of knowledge between mitochondrial physiology, liver metabolic flux control and oxidative stress and deepen our insight on how mitochondrial damage disrupts the control of hepatic glucose and lipid fluxes. Three host institutions are involved in WP2 (NENCKI, CNR and INSERM), since they have the necessary expertise, training experience and technology needed for the three projects.