Adriana Filipa Fontes ESR12 (Helmholtz Zentrum München, Germany) was doing her eight-month secondment at the Mitochondrial Toxicology and Experimental Therapeutics (MitoXT laboratory) at CNC UC, Portugal. The focus of her work was to determine the effects of mushrooms extracts in fat accumulation in a hepatic cancer cell line (HepG2) in regards to cell viability, cell mass alterations and mitochondria function and to understand if the mushrooms extracts have the capacity to decrease the accumulation of fat (steatosis) in this cell line. The importance of this work lies in the screening of initial seven mushrooms species to choose the most promising for in vivo studies.